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MR 1.2.2566-09

МР 1.2.2566-09

Evaluation of the safety of nanomaterials in vitro and in vivo model systems

Оценка безопасности наноматериалов in vitro и в модельных системах in vivo

Status: Effective - Introduced for the first time

These guidelines are used to test the safety of nanoparticles and artificial nanomaterials on model biological objects, including cultures of symbiotic, conditionally pathogenic and pathogenic microorganisms, cell cultures of various tissues of higher animals, hydrobionts (crustaceans, fish), organisms of laboratory animals.

Настоящие методические рекомендации используются при проведении тестирования безопасности наночастиц и наноматериалов искусственного происхождения на модельных биологических объектах, включая культуры симбиотических, условно патогенных и патогенных микроорганизмов, культуры клеток различных тканей высших животных, гидробионты (ракообразные, рыбы), организмы лабораторных животных.

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Format: Electronic (pdf/doc)

Approved: Chief State Sanitary Doctor of the Russian Federation, 12/10/2009

SKU: RUSS155031

Price: $662.00



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The Product is Contained in the Following Classifiers:

PromExpert » SECTION III. LABOR PROTECTION AND SAFETY » II Industrial sanitation and occupational health » 1 General requirements for occupational health and hygiene »

ISO classifier » 11 HEALTH » 11.020 Medical sciences and health care conditions in general »


The Document References:

Federal Law 52-FZ: Public Sanitary and Epidemiological Well-Being

Federal Law 7-FZ: Environmental Protection

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GOST 112-78: Meteorological glass thermometers

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GOST 20015-88: Chloroform. Specifications

GOST 21239-93: Instruments for surgery. Scissors. General requirements and test methods

GOST 21240-89: Medical scalpels and knives

GOST 21241-89: Medical pincers

GOST 2156-76: Sodium bicarbonate. Technical conditions

GOST 2222-95: Technical methanol. Specifications

GOST 23519-79: Phenol synthetic technical. Specifications

GOST 24104-2001: Laboratory scales. General technical requirements

GOST 25336-82: Laboratory glassware and equipment. Basic parameters and dimensions

GOST 26678-85: Domestic electrical compression refrigerators and deepfreezes of product line

GOST 27987-88: Potentiometric analyzer of liquid, SSI. General specifications

GOST 29227-91: Laboratory glassware. Graduated pipettes. Part 1. General requirements

GOST 30333-95: Substance (material) safety passport. Basic principles. Information on material safety at manufacturing, utilization, storage, transportation and disposal handling

GOST 3117-78: Reagents. Ammonium acetate. Specifications

GOST 3164-78: Medical petrolatum. Specifications

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GOST 4209-77: Reagents. Magnesium chloride 6-aqueous. Specifications

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GOST 4403-91: Fabrics of silk and synthetic threads for sieves. General specifications

GOST 4568-95: Potassium chloride

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GOST 9147-80: Laboratory porcelain ware and apparatus. Specifications

GOST 9805-84: Isopropyl alcohol. Specifications

GOST R 51232-98: Drinking water. General requirements for organization and quality control methods

GOST R 51652-2000: Rectified ethyl alcohol of food raw material. Specifications

MU 1.2.2520-09: Toxicological and hygienic safety assessment of nanomaterials

The Document is Referenced By:

MR 1.2.0022-11: Sampling procedure for nanomaterials control

MR 1.2.0023-11: Control of nanomaterials in the food industry

MR 1.2.0024-11: Control of nanomaterials used in the chemical industry

MR 1.2.0036-11: Control of nanomaterials in disinfectants and household chemicals

MR 1.2.0038-11: Evaluation of the risk of exposure of the human body to nanomaterials and nanoparticles

MR 1.2.0039-11: Control nanomaterials in packaging materials

MR 1.2.0040-11: Control of nanomaterials in the perfumery and cosmetic industry

MR 1.2.0041-11: The decision-making system for the control of nano-safety based on an assessment of the risks of production, use and recycling of nanomaterials based on monitoring of these processes at nano-industry enterprises

MR 1.2.0042-11: Control of nanomaterials used in agriculture

MR 1.2.0044-11: The procedure for identifying and identifying fullerene C60 aggregates in animal and plant tissue sections by analytical electron microscopy

MR 1.2.0045-11: The procedure for the detection and identification of multi-walled carbon nanotubes in sections of animal and plant tissues by analytical electron microscopy

MR 1.2.0046-11: The use of the energy dispersive microspectroscopy method for the analysis of silver nanoparticles, zinc, aluminum and cerium oxides in animal and plant tissues

MR 1.2.0047-11: Electron microscopy detection of structural changes caused by artificial nanoparticles in animal and plant cells

MR 1.2.0052-11: Evaluation of the Impact of Nanomaterials on Immunity Function

MR 1.2.0053-11: Evaluation of the effects of nanomaterials on the proteomic profile and biosynthetic processes in tests on laboratory animals

MR 1.2.0054-11: The procedure and methods for evaluating the effects of artificial nanoparticles and nanomaterials on the toxic effects of chemicals

MR 1.2.2640-10: Sampling methods, detection and determination of the content of nanoparticles and nanomaterials in the composition of agricultural, food products and packaging materials

MU 1.2.2637-10: Procedure and methods of control of nanoparticles migration from packaging

MU 1.2.2740-10: Sampling procedure for identifying, identifying and characterizing the action of nanomaterials in aquatic invertebrates

MU 1.2.2741-10: Sampling procedure for the identification and identification of nanomaterials in laboratory animals

MU 1.2.2744-10: Sampling procedure for the identification and identification of nanomaterials in fish

MU 1.2.2745-10: Sampling procedure for characterizing the action of nanomaterials on laboratory animals

MU 1.2.2869-11: The procedure for assessing the toxic effects of nanomaterials on laboratory animals

MU 1.2.2874-11: The procedure for the identification and identification of nanomaterials in laboratory animals

MU 1.2.2875-11: The procedure for the identification and identification of nanomaterials in water bodies

MU 1.2.2877-11: The procedure for the identification and identification of nanomaterials in fish

MU 1.2.2966-11: The procedure and organization of control over nanomaterials

MU 1.2.2967-11: The procedure for assessing the effect of nanomaterials on fish on the basis of morphological and genetic features.

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