MU 1.2.2520-09
МУ 1.2.2520-09
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Toxicological and hygienic safety assessment of nanomaterials
Токсиколого-гигиеническая оценка безопасности наноматериалов
Status: Effective - Introduced for the first time
Guidelines establish requirements for conducting toxicological and hygienic studies to assess the safety of nanomaterials. The requirements set forth in the guidelines are applied in the implementation of state registration of products obtained using nanotechnology or containing nanomaterials, first developed and introduced for industrial manufacturing in the Russian Federation at the stage of its preparation for production, as well as for the first time imported and not previously implemented its importation into the territory of the Russian Federation. Guidelines are designed to provide a unified, scientifically based system of toxicological and hygienic safety assessment of nanomaterials. Guidelines are intended for specialists of bodies and organizations of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, and can also be used by research organizations of hygienic profile, medical educational institutions and other organizations and institutions accredited in due course.
Методические указания устанавливают требования к проведению токсиколого-гигиенических исследований по оценке безопасности наноматериалов. Требования, изложенные в методических указаниях, применяются при осуществлении государственной регистрации продукции, полученной с использованием нанотехнологий или содержащей наноматериалы, впервые разрабатываемой и внедряемой для промышленного изготовления на территории Российской Федерации на этапе ее подготовки к производству, а также впервые ввозимой и ранее не реализовывавшейся - до ее ввоза на территорию Российской Федерации. Методические указания разработаны с целью обеспечения единой, научно обоснованной системы токсиколого-гигиенической оценки безопасности наноматериалов. Методические указания предназначены для специалистов органов и организаций Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека, а также могут быть использованы научно-исследовательскими организациями гигиенического профиля, медицинскими учебными заведениями и иными организациями и учреждениями, аккредитованными в установленном порядке.
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Format: Electronic (pdf/doc)
Approved: Head of the Federal Service for Supervision of Consumer Rights Protection and Human Well-being, Chief State Sanitary Doctor of the Russian Federation,
6/5/2009
SKU: RUSS155638
The Product is Contained in the Following Classifiers:
Construction (Max) »
Regulations »
Regulatory documents of supervisory authorities »
Normative documents of State Committee for Sanitary and Epidemiological Supervision and Ministry of Health of Russian Federation »
PromExpert »
SECTION III. LABOR PROTECTION AND SAFETY »
II Industrial sanitation and occupational health »
1 General requirements for occupational health and hygiene »
ISO classifier »
11 HEALTH »
11.020 Medical sciences and health care conditions in general »
The Document References:
Federal Law 184-FZ: About technical regulation
Federal Law 52-FZ: Public Sanitary and Epidemiological Well-Being
Federal Law 7-FZ: Environmental Protection
The Document is Referenced By:
GOST R 57933-2017: Nanotechnologies. Nanomaterials. Toxicological and hygienic safety assessment. General requirements for testing on laboratory animals
MR 1.2.0016-10: Classification of nanotechnologies and nanoindustry products by the degree of their potential danger
MR 1.2.0018-11: Sampling procedure and methods for determining the content of nanoparticles in the composition of household chemical products, disinfectants and perfumes and cosmetics
MR 1.2.0022-11: Sampling procedure for nanomaterials control
MR 1.2.0023-11: Control of nanomaterials in the food industry
MR 1.2.0024-11: Control of nanomaterials used in the chemical industry
MR 1.2.0037-11: Control of nanomaterials in the air
MR 1.2.0038-11: Evaluation of the risk of exposure of the human body to nanomaterials and nanoparticles
MR 1.2.0039-11: Control nanomaterials in packaging materials
MR 1.2.0040-11: Control of nanomaterials in the perfumery and cosmetic industry
MR 1.2.0041-11: The decision-making system for the control of nano-safety based on an assessment of the risks of production, use and recycling of nanomaterials based on monitoring of these processes at nano-industry enterprises
MR 1.2.0042-11: Control of nanomaterials used in agriculture
MR 1.2.0043-11: Control of nanomaterials in the environment
MR 1.2.0044-11: The procedure for identifying and identifying fullerene C60 aggregates in animal and plant tissue sections by analytical electron microscopy
MR 1.2.0045-11: The procedure for the detection and identification of multi-walled carbon nanotubes in sections of animal and plant tissues by analytical electron microscopy
MR 1.2.0046-11: The use of the energy dispersive microspectroscopy method for the analysis of silver nanoparticles, zinc, aluminum and cerium oxides in animal and plant tissues
MR 1.2.0047-11: Electron microscopy detection of structural changes caused by artificial nanoparticles in animal and plant cells
MR 1.2.0048-11: The procedure and methods for determining the organotropic and toxicokinetic parameters of artificial nanomaterials in tests on laboratory animals
MR 1.2.0052-11: Evaluation of the Impact of Nanomaterials on Immunity Function
MR 1.2.0053-11: Evaluation of the effects of nanomaterials on the proteomic profile and biosynthetic processes in tests on laboratory animals
MR 1.2.0054-11: The procedure and methods for evaluating the effects of artificial nanoparticles and nanomaterials on the toxic effects of chemicals
MR 1.2.2522-09: Recommended practice for identification of finanomaterials that pose a potential risk to human health
MR 1.2.2566-09: Evaluation of the safety of nanomaterials in vitro and in vivo model systems
MR 1.2.2640-10: Sampling methods, detection and determination of the content of nanoparticles and nanomaterials in the composition of agricultural, food products and packaging materials
MR 1.2.2641-10: Determination of priority types of nanomaterials in environmental objects, living organisms and food products
MR 4.2.0014-10: Methods of control. Biological factors. Evaluation of genotoxic properties by the method of DNA comets in vitro
MU 1.2.2634-10: Microbiological and molecular genetic assessment of the effects of nanomaterials on microbiocenosis representatives
MU 1.2.2635-10: Medical and biological evaluation of nanomaterials safety
MU 1.2.2636-10: Sanitary-epidemiological examination of products produced by using nanotechnology and nanomaterials
MU 1.2.2637-10: Procedure and methods of control of nanoparticles migration from packaging
MU 1.2.2638-10: Safety assessment of packaging materials contacting with food obtained by use of nanotechnology
MU 1.2.2740-10: Sampling procedure for identifying, identifying and characterizing the action of nanomaterials in aquatic invertebrates
MU 1.2.2741-10: Sampling procedure for the identification and identification of nanomaterials in laboratory animals
MU 1.2.2744-10: Sampling procedure for the identification and identification of nanomaterials in fish
MU 1.2.2745-10: Sampling procedure for characterizing the action of nanomaterials on laboratory animals
MU 1.2.2869-11: The procedure for assessing the toxic effects of nanomaterials on laboratory animals
MU 1.2.2873-11: The procedure for the identification and identification of nanomaterials in aquatic invertebrates
MU 1.2.2874-11: The procedure for the identification and identification of nanomaterials in laboratory animals
MU 1.2.2875-11: The procedure for the identification and identification of nanomaterials in water bodies
MU 1.2.2876-11: The procedure for the identification and identification of nanomaterials in plants
MU 1.2.2877-11: The procedure for the identification and identification of nanomaterials in fish
MU 1.2.2966-11: The procedure and organization of control over nanomaterials
MU 1.2.2967-11: The procedure for assessing the effect of nanomaterials on fish on the basis of morphological and genetic features.
MU 1.2.2968-11: The order of biological assessment of the effects of nanomaterials on plants according to morphological features. Methodical instructions
MU 1.2.3216-14: Evaluation of the risk of exposure of the population to pesticide residues in food
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