MU 1.2.2745-10
МУ 1.2.2745-10
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Sampling procedure for characterizing the action of nanomaterials on laboratory animals
Порядок отбора проб для характеристики действия наноматериалов на лабораторных животных
Status: Effective - Introduced for the first time
Guidelines establish requirements for sampling methods to characterize the effects of nanomaterials on laboratory animals, taking into account data on the pathways of nanomaterials entering the body and the intended target organs of their effects. The requirements set forth in the guidelines are applied in the course of toxicological, hygienic and biomedical guidance on the safety of nanomaterials in order to make decisions on the assessment of risks associated with the effects of nanoparticles and nanomaterials on the human body. Guidelines are designed to ensure the unity of methods and means of sampling during the assessment of the safety of nanomaterials and nanotechnologies for human health and components of natural biocenoses. Guidelines are intended for specialists of bodies and institutions of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, and can also be used by research organizations of hygienic profile, medical schools and other organizations and institutions conducting studies on the safety assessment of nanomaterials.
Методические указания устанавливают требования к методам отбора проб для характеристики действия наноматериалов на лабораторных животных с учетом данных о путях поступления наноматериалов в организм и предполагаемых органах-мишенях их воздействия. Требования, изложенные в методических указаниях, применяются в ходе проведения токсиколого-гигиенических и медико-биологических оценок безопасности наноматериалов в целях принятия решений по оценке рисков, связанных с воздействием наночастиц и наноматериалов на организм человека. Методические указания разработаны с целью обеспечения единства методов и средств отбора проб в ходе оценки безопасности наноматериалов и нанотехнологий для состояния здоровья человека и компонентов естественных биоценозов. Методические указания предназначены для специалистов органов и учреждений Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека, а также могут быть использованы научно-исследовательскими организациями гигиенического профиля, медицинскими учебными заведениями и иными организациями и учреждениями, проводящими исследования по оценке безопасности наноматериалов.
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Format: Electronic (pdf/doc)
Approved: Chief State Sanitary Doctor of the Russian Federation,
9/23/2010
SKU: RUSS155645
The Product is Contained in the Following Classifiers:
PromExpert »
SECTION III. LABOR PROTECTION AND SAFETY »
II Industrial sanitation and occupational health »
1 General requirements for occupational health and hygiene »
ISO classifier »
11 HEALTH »
11.020 Medical sciences and health care conditions in general »
ISO classifier »
11 HEALTH »
11.220 Veterinary Medicine »
The Document References:
Federal Law 184-FZ: About technical regulation
Federal Law 29-FZ: About quality and food safety
Federal Law 52-FZ: Public Sanitary and Epidemiological Well-Being
Federal Law 7-FZ: Environmental Protection
GOST 12.1.004-91: Fire safety. General requirements
GOST 12.1.007-76: Noxious substances. Classification and general safety requirements
GOST 12.2.003-91: Industrial equipment. General safety requirements
GOST 12.2.052-81: Occupational safety standards system. Equipment working with gaseous oxygen. General safety requirements
GOST 1770-74: Laboratory volumetric glassware. Cylinders, beakers, measuring flasks, test tubes. General specifications
GOST 20015-88: Chloroform. Specifications
GOST 21239-93: Instruments for surgery. Scissors. General requirements and test methods
GOST 21241-89: Medical pincers
GOST 24104-2001: Laboratory scales. General technical requirements
GOST 2493-75: Reagents. Potassium phosphate, dibasic 3-aqueous. Specifications
GOST 25336-82: Laboratory glassware and equipment. Basic parameters and dimensions
GOST 26678-85: Domestic electrical compression refrigerators and deepfreezes of product line
GOST 30393-95: Surgical instruments. Scalpels with detachable blades. Fitting dimensions
GOST 3-88: Surgical rubber gloves
GOST 4172-76: Reagents. Disodium hydrogen phosphate dodecahydrate. Specification
GOST 4198-75: Reagents. Potassium dihydrogen phosphate. Specifications
GOST 4199-76: Reagents. 10-aqueous sodium tetraborate. Specifications
GOST 4233-77: Reagents. Sodium chloride. Specifications
GOST 5833-75: Reagents. Saccharose. Specifications
GOST 6259-75: Reagents. Glycerin. Specifications
GOST 8.207-76: Direct measurements with multiple observations. Observation data processing methods
GOST 9293-74: Gaseous and liquid nitrogen. Specifications
GOST 9656-75: Reagents. Boric acid. Specifications
GOST R 50444-92: Medical instruments, apparatus and equipment. General specifications
GOST R 51350-99: Safety requirements for electrical equipment for measurement, control, and laboratory use. Part 1. General requirements
GOST R 51652-2000: Rectified ethyl alcohol of food raw material. Specifications
GOST R ISO/IEC 17025-2006: General requirements for the competence of testing and calibration laboratories
MR 1.2.2522-09: Recommended practice for identification of finanomaterials that pose a potential risk to human health
MR 1.2.2566-09: Evaluation of the safety of nanomaterials in vitro and in vivo model systems
MU 1.2.2520-09: Toxicological and hygienic safety assessment of nanomaterials
MU 1.3.2569-09: Organization of work of laboratories using nucleic acid amplification methods when working with material containing microorganisms of patches of groups I - IV
MU 4.2.2039-05: Technics of gathering and transportation of biomaterials to microbiological laboratories
Resolution 322: Regulations on the Federal Service for Supervision of Consumer Rights Protection and Human Welfare
SanPiN 2.1.7.1322-03: Hygienic requirements regarding dumping and decontamination of industrial and consumable waste
SP 1.2.036-95: Order of calculation, storage, transfer and transportation of the microorganisms of I-IV PAthogenicity groups
SP 1.3.2322-08: Safety of work with microorganisms of III-IV groups of pathogenicity (hazard) and agent of parasitogenic diseases
SP 2.2.2.1327-03: Hygienic regulations for organization of technological processes, production equipment and working instrument
The Document is Referenced By:
MU 1.2.2874-11: The procedure for the identification and identification of nanomaterials in laboratory animals
MU 1.2.2966-11: The procedure and organization of control over nanomaterials
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